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Murine Polyomavirus encodes a microRNA that cleaves early RNA transcripts but is not essential for experimental infection

MicroRNAs are small regulatory RNAs that post-transcriptionally regulate gene expression and can be encoded by viral as well as cellular genomes. The functions of most viral miRNAs are unknown and few have been studied in an in vivo context. Here we show that the murine polyomavirus (PyV) encodes a...

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Detalhes bibliográficos
Main Authors: Sullivan, Christopher S., Sung, Chang K., Pack, Christopher D., Grundhoff, Adam, Lukacher, Aron E., Benjamin, Thomas L., Ganem, Don
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722155/
https://ncbi.nlm.nih.gov/pubmed/19272626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.02.017
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