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Essential role of TGF-β signaling in glucose-induced cell hypertrophy

In multicellular organisms, cell size is tightly controlled by nutrients and growth factors. Increasing ambient glucose induces enhanced protein synthesis and cell size. Continued exposure of cells to high glucose in vivo, as apparent under pathological conditions, results in cell hypertrophy and ti...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wu, Liyu, Derynck, Rik
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722039/
https://ncbi.nlm.nih.gov/pubmed/19619490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.05.010
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