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Essential role of TGF-β signaling in glucose-induced cell hypertrophy

In multicellular organisms, cell size is tightly controlled by nutrients and growth factors. Increasing ambient glucose induces enhanced protein synthesis and cell size. Continued exposure of cells to high glucose in vivo, as apparent under pathological conditions, results in cell hypertrophy and ti...

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Detalhes bibliográficos
Main Authors: Wu, Liyu, Derynck, Rik
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722039/
https://ncbi.nlm.nih.gov/pubmed/19619490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.05.010
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