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Molecular Karyotype of Sporadic Unilateral Retinoblastoma Tumors

BACKGROUND: Retinoblastoma (RB) is a childhood ocular malignancy associated with mutations in RB1, a tumor susceptibility gene. Inactivation of both copies of the RB1 gene in a retinal cell is followed by the sequential acquisition of additional genetic changes that define the course to tumor format...

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Detalhes bibliográficos
Main Authors: Ganguly, Arupa, Nichols, Kim E., Grant, Gregory, Rappaport, Eric, Shields, Carol
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722034/
https://ncbi.nlm.nih.gov/pubmed/19491728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/IAE.0b013e3181a0be05
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