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TLI and ATG conditioning with low risk of graft-versus-host disease retains antitumor reactions after allogeneic hematopoietic cell transplantation from related and unrelated donors

A hematopoietic cell transplantation regimen was adapted from a preclinical model that used reduced-intensity conditioning (RIC) and protected against graft-versus-host disease (GVHD) by skewing residual host T-cell subsets to favor regulatory natural killer T cells. One hundred eleven patients with...

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Autori principali: Kohrt, Holbrook E., Turnbull, Brit B., Heydari, Kartoosh, Shizuru, Judith A., Laport, Ginna G., Miklos, David B., Johnston, Laura J., Arai, Sally, Weng, Wen-Kai, Hoppe, Richard T., Lavori, Philip W., Blume, Karl G., Negrin, Robert S., Strober, Samuel, Lowsky, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721787/
https://ncbi.nlm.nih.gov/pubmed/19423725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-211441
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