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HLA-mismatched unrelated donor transplantation using TLI-ATG conditioning has a low risk of GVHD and potent antitumor activity

Many patients lack a fully HLA-matched donor for hematopoietic cell transplantation (HCT), and HLA mismatch is typically associated with inferior outcomes. Total lymphoid irradiation and antithymocyte globulin (TLI-ATG) is a nonmyeloablative conditioning regimen that is protective against graft-vers...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Spinner, Michael A., Fernández-Viña, Marcelo, Creary, Lisa E., Quinn, Olivia, Elder, Linda, Arai, Sally, Johnston, Laura J., Meyer, Everett H., Miklos, David B., Muffly, Lori S., Negrin, Robert S., Shizuru, Judith A., Weng, Wen-Kai, Laport, Ginna G., Strober, Samuel, Lowsky, Robert, Rezvani, Andrew R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727975/
https://ncbi.nlm.nih.gov/pubmed/29296777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017007716
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