Structure-activity relationships of anthraquinone derivatives derived from bromaminic acid as inhibitors of ectonucleoside triphosphate diphosphohydrolases (E-NTPDases)

Reactive blue 2 (RB-2) had been characterized as a relatively potent ectonucleoside triphosphate diphosphohydrolase (E-NTPDase) inhibitor with some selectivity for NTPDase3. In search for the pharmacophore and to analyze structure-activity relationships we synthesized a series of truncated derivativ...

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Detalhes bibliográficos
Main Authors: Baqi, Younis, Weyler, Stefanie, Iqbal, Jamshed, Zimmermann, Herbert, Müller, Christa E.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2008
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721768/
https://ncbi.nlm.nih.gov/pubmed/18528783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-008-9103-5
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