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Adaptive ligand binding by the purine riboswitch in the recognition of guanine and adenine analogs

Purine riboswitches discriminate between guanine and adenine by at least 10,000-fold based on the identity of a single pyrimidine (Y74) that forms a Watson-Crick base pair with the ligand. To understand how this high degree of specificity for closely related compounds is achieved through simple pair...

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Detaylı Bibliyografya
Asıl Yazarlar: Gilbert, Sunny D., Reyes, Francis E., Edwards, Andrea L., Batey, Robert T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721690/
https://ncbi.nlm.nih.gov/pubmed/19523903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.04.009
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