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Double-Stranded RNA–Activated Protein Kinase Mediates Induction of Interleukin-8 Expression by Deoxynivalenol, Shiga Toxin 1, and Ricin in Monocytes

Translational inhibitors such as the trichothecene mycotoxin deoxynivalenol (DON) and ribosomal inhibitory proteins (RIPs) induce mitogen-activated protein kinase (MAPK)–driven chemokine and cytokine production by a mechanism known as the ribotoxic stress response (RSR). Double-stranded RNA–activate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gray, Jennifer S., Bae, Hee Kyong, Li, James C. B., Lau, Allan S., Pestka, James J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721672/
https://ncbi.nlm.nih.gov/pubmed/18599499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfn128
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