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Double-Stranded RNA–Activated Protein Kinase Mediates Induction of Interleukin-8 Expression by Deoxynivalenol, Shiga Toxin 1, and Ricin in Monocytes
Translational inhibitors such as the trichothecene mycotoxin deoxynivalenol (DON) and ribosomal inhibitory proteins (RIPs) induce mitogen-activated protein kinase (MAPK)–driven chemokine and cytokine production by a mechanism known as the ribotoxic stress response (RSR). Double-stranded RNA–activate...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2721672/ https://ncbi.nlm.nih.gov/pubmed/18599499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfn128 |
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