Potential Neurotoxicity of Ketamine in the Developing Rat Brain

Ketamine, an N-methyl-D-aspartate (NMDA) receptor ion channel blocker, is a widely used anesthetic recently reported to enhance neuronal death in developing rodents and nonhuman primates. This study evaluated dose-response and time-course effects of ketamine, levels of ketamine in plasma and brain,...

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Bibliographische Detailangaben
Hauptverfasser: Zou, Xiaoju, Patterson, Tucker A., Sadovova, Natalya, Twaddle, Nathan C., Doerge, Daniel R., Zhang, Xuan, Fu, Xin, Hanig, Joseph P., Paule, Merle G., Slikker, William, Wang, Cheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
Schlagworte:
Neurotoxicology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721655/
https://ncbi.nlm.nih.gov/pubmed/19126600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfn270
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