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Evidence for involvement of nonesterified fatty acid-induced protonophoric uncoupling during mitochondrial dysfunction caused by hypoxia and reoxygenation

Background. Proximal tubules subjected to hypoxia in vitro under conditions relevant to ischaemia in vivo develop an energetic deficit that is not corrected even after full reoxygenation. We have provided evidence that accumulation of nonesterified fatty acids (NEFA) is the primary reason for this e...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Feldkamp, Thorsten, Weinberg, Joel M., Hörbelt, Markus, Von Kropff, Christina, Witzke, Oliver, Nürnberger, Jens, Kribben, Andreas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721422/
https://ncbi.nlm.nih.gov/pubmed/18678559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfn436
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