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Natalizumab for the treatment of relapsing multiple sclerosis

Natalizumab is an α4-integrin antagonist approved as monotherapy for patients with relapsing multiple sclerosis (MS), based on demonstrated efficacy in the pivotal AFFIRM study (N = 942). Natalizumab monotherapy reduced risk of disability progression by 42%–54% and annualized relapse rate by 68% dur...

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Detalhes bibliográficos
Main Authors: Rudick, Richard A, Panzara, Michael A
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721353/
https://ncbi.nlm.nih.gov/pubmed/19707353
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