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Natalizumab: A new treatment for relapsing remitting multiple sclerosis

Natalizumab, a new disease-modifying therapy for relapsing remitting multiple sclerosis (RRMS), is a humanized monoclonal antibody which binds to α(4)β(1)-integrin. In a Phase 3 trial, 2 years of natalizumab monotherapy reduced the mean annualized relapse rate (ARR) by 68% compared with placebo (p &...

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Bibliografske podrobnosti
Glavni avtor: Hutchinson, Michael
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1936307/
https://ncbi.nlm.nih.gov/pubmed/18360634
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