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Control of the reversibility of cellular quiescence by the transcriptional repressor HES1

The mechanisms by which quiescent cells, including adult stems cells, preserve their ability to resume proliferation after weeks or even years of cell cycle arrest are not known. We report that reversibility is not a passive property of non-dividing cells, because enforced cell cycle arrest for a pe...

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Detalhes bibliográficos
Main Authors: Sang, Liyun, Coller, Hilary A., Roberts, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721335/
https://ncbi.nlm.nih.gov/pubmed/18719287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1155998
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