The Hexosamine Template – A Platform for Modulating Gene Expression and for Sugar-based Drug Discovery

This study investigates the breadth of cellular responses engendered by short chain fatty acid (SCFA)-hexosamine hybrid molecules, a class of compounds long used in ‘metabolic glycoengineering’ that are now emerging as drug candidates. First, a ‘mix-and-match’ strategy showed that different SCFA (n-...

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Hlavní autoři: Elmouelhi, Noha, Aich, Udayanath, Paruchuri, Venkata D.P., Meledeo, M. Adam, Campbell, Christopher T., Wang, Jean J., Srinivas, Raja, Khanna, Hargun S., Yarema, Kevin J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721157/
https://ncbi.nlm.nih.gov/pubmed/19326913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm801661m
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