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Metabolic Oligosaccharide Engineering with N-Acyl Functionalized ManNAc Analogues: Cytotoxicity, Metabolic Flux, and Glycan-display Considerations

Metabolic oligosaccharide engineering is a maturing technology capable of modifying cell surface sugars in living cells and animals through the biosynthetic installation of non-natural monosaccharides into the glycocalyx. A particularly robust area of investigation involves the incorporation of azid...

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Hlavní autoři: Almaraz, Ruben T., Aich, Udayanath, Khanna, Hargun S., Tan, Elaine, Bhattacharya, Rahul, Shah, Shivam, Yarema, Kevin J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288793/
https://ncbi.nlm.nih.gov/pubmed/22068462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.24363
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