TrkB Signaling Is Required for Both the Induction and Maintenance of Tissue and Nerve Injury-Induced Persistent Pain

Activation of primary afferent nociceptors produces acute, short-lived pain, and tissue or nerve injury induces long-term enhancement of nociceptive processing, manifested as hypersensitivity to thermal and mechanical stimulation. Here we used a chemical–genetic and pharmacological approach to study...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Xidao, Ratnam, Joseline, Zou, Bende, England, Pamela M., Basbaum, Allan I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2009
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720992/
https://ncbi.nlm.nih.gov/pubmed/19403818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4288-08.2009
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