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KRAB zinc-finger proteins localise to novel KAP1-containing foci that are adjacent to PML nuclear bodies

The KRAB-zinc finger proteins (KRAB-ZFPs) represent a very large, but poorly understood, family of transcriptional regulators in mammals. They are thought to repress transcription via their interaction with KRAB-associated protein 1 (KAP1), which then assembles a complex of chromatin modifiers to la...

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Main Authors: Briers, Stephanie, Crawford, Catherine, Bickmore, Wendy A., Sutherland, Heidi G.
格式: Artigo
語言:Inglês
出版: Company of Biologists 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720929/
https://ncbi.nlm.nih.gov/pubmed/19258395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.034793
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