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In Vitro Fidelity of the prototype primate foamy virus (PFV) RT compared to HIV-1 RT

We compared the in vitro fidelity of wild-type human immunodeficiency virus type-1 (HIV-1) reverse transcriptase (RT) and the prototype foamy virus (PFV) RT. Both enzymes had similar error rates for single nucleotide substitutions; however, PFV RT did not appear to make errors at specific hotspots,...

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Hlavní autoři: Boyer, Paul L., Stenbak, Carolyn R., Hoberman, David, Linial, Maxine L., Hughes, Stephen H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720797/
https://ncbi.nlm.nih.gov/pubmed/17631930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.05.034
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