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In Vitro Fidelity of the prototype primate foamy virus (PFV) RT compared to HIV-1 RT
We compared the in vitro fidelity of wild-type human immunodeficiency virus type-1 (HIV-1) reverse transcriptase (RT) and the prototype foamy virus (PFV) RT. Both enzymes had similar error rates for single nucleotide substitutions; however, PFV RT did not appear to make errors at specific hotspots,...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2720797/ https://ncbi.nlm.nih.gov/pubmed/17631930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.05.034 |
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