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Prediction of drug response in breast cancer using integrative experimental/computational modeling

Nearly 30% of women with early stage breast cancer develop recurrent disease attributed to resistance to systemic therapy. Prevailing models of chemotherapy failure describe three resistant phenotypes: cells with alterations in transmembrane drug transport, increased detoxification and repair pathwa...

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Bibliografski detalji
Glavni autori: Frieboes, Hermann B., Edgerton, Mary E., Fruehauf, John P., Rose, Felicity R. A. J., Worrall, Lisa K., Gatenby, Robert A., Ferrari, Mauro, Cristini, Vittorio
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720602/
https://ncbi.nlm.nih.gov/pubmed/19366802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3740
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