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Genetic Heterogeneity in Severe Congenital Neutropenia: How Many Aberrant Pathways Can Kill a Neutrophil?

PURPOSE OF REVIEW: Severe congenital neutropenia (SCN) is a primary immunodeficiency in which lack of neutrophils causes inadequate innate immune host response to bacterial infections. SCN occurs with sporadic, autosomal dominant (AD), autosomal recessive (AR), and X-linked recessive (XLR) inheritan...

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Detalhes bibliográficos
Main Authors: Schäffer, Alejandro A., Klein, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720578/
https://ncbi.nlm.nih.gov/pubmed/17989524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ACI.0b013e3282f1d690
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