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Bax-Induced Apoptosis in Leber's Congenital Amaurosis: A Dual Role in Rod and Cone Degeneration
Pathogenesis in the Rpe65(−/−) mouse model of Leber's congenital amaurosis (LCA) is characterized by a slow and progressive degeneration of the rod photoreceptors. On the opposite, cones degenerate rapidly at early ages. Retinal degeneration in Rpe65 (−/−) mice, showing a null mutation in the g...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2720534/ https://ncbi.nlm.nih.gov/pubmed/19672311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006616 |
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