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Striking the balance between PTEN and PDK1: it all depends on the cell context
The phosphatidyl-inosital-3 kinase (PI3K) signaling pathway is critical for normal brain development and function and is commonly hyperactivated in brain cancer. The PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor protein and phosphate-depended kinase 1 (PDK-1) are cr...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2720262/ https://ncbi.nlm.nih.gov/pubmed/19651981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1832909 |
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