The Down syndrome critical region gene 1 short variant promoters direct vascular bed–specific gene expression during inflammation in mice

Down syndrome critical region gene 1 (DSCR-1) short variant (DSCR-1s) is an inhibitor of calcineurin/NFAT signaling encoded by exons 4–7 of DSCR1. We previously reported that VEGF induces DSCR-1s expression in endothelial cells, which in turn negatively feeds back to attenuate endothelial cell activ...

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Détails bibliographiques
Auteurs principaux: Minami, Takashi, Yano, Kiichiro, Miura, Mai, Kobayashi, Mika, Suehiro, Jun-ichi, Reid, Patrick C., Hamakubo, Takao, Ryeom, Sandra, Aird, William C., Kodama, Tatsuhiko
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2009
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719921/
https://ncbi.nlm.nih.gov/pubmed/19620774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35738
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