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Benchmarking Implicit Solvent Folding Simulations of the Amyloid β(10–35) Fragment

A pathogenetic feature of Alzhemier disease is the aggregation of monomeric β-amyloid proteins (Aβ) to form oligomers. Usually these oligomers of long peptides aggregate on time scales of microseconds or longer, making computational studies using atomistic molecular dynamics models prohibitively exp...

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Bibliografiset tiedot
Päätekijät: Kent, Andrew, Jha, Abhishek K, Fitzgerald, James E, Freed, Karl F
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719849/
https://ncbi.nlm.nih.gov/pubmed/18348560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp077099h
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