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Keratinocyte-Derived Chemokine Induces Prostate Epithelial Hyperplasia and Reactive Stroma in a Novel Transgenic Mouse Model

BACKGROUND: Interleukin-8 (IL-8) is upregulated in fibrotic and malignant diseases and is a key mediator of proliferative responses. Elevated IL-8 was recently correlated with benign prostatic hyperplasia epithelium and a myofibroblast reactive stroma. Thus, we sought to determine whether overexpres...

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Detalhes bibliográficos
Main Authors: Schauer, Isaiah G., Ressler, Steven J., Rowley, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719820/
https://ncbi.nlm.nih.gov/pubmed/19021203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.20886
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