A carregar...
Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants
The molecular mechanism by which mutations in the cytoskeleton-organizing protein PSTPIP1 cause the autoinflammatory PAPA syndrome is still elusive. Here, we demonstrate that PSTPIP1 requires the Familial Mediterranean Fever protein pyrin to assemble the ASC pyroptosome, a molecular platform that re...
Na minha lista:
| Main Authors: | , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2719761/ https://ncbi.nlm.nih.gov/pubmed/17964261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.08.029 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|