The two-pore channel TPCN2 mediates NAADP-dependent Ca(2+)-release from lysosomal stores

Second messenger-induced Ca(2+)-release from intracellular stores plays a key role in a multitude of physiological processes. In addition to 1,4,5-inositol trisphosphate (IP(3)), Ca(2+), and cyclic ADP ribose (cADPR) that trigger Ca(2+)-release from the endoplasmatic reticulum (ER), nicotinic acid a...

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Detalhes bibliográficos
Main Authors: Zong, Xiangang, Schieder, Michael, Cuny, Hartmut, Fenske, Stefanie, Gruner, Christian, Rötzer, Katrin, Griesbeck, Oliver, Harz, Hartmann, Biel, Martin, Wahl-Schott, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2009
Assuntos:
Ion Channels, Receptors and Transporters
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719734/
https://ncbi.nlm.nih.gov/pubmed/19557428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-009-0690-y
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