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Regulation of intracellular calcium in cortical neurons transgenic for human Aβ40 and Aβ42 following nutritive challenge

The pathogenesis of Alzheimer's Disease (AD) is not fully understood. Amyloid plaques could be causally linked to neuronal loss in AD. Two proteolytic products of the Amyloid Precursor Protein (APP), Amyloid β40 (Aβ40) and Amyloid β42 (Aβ42), are considered to be critical in the neurodegenerati...

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Detalhes bibliográficos
Main Authors: Shirwany, Najeeb A, Xie, Jun, Guo, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719704/
https://ncbi.nlm.nih.gov/pubmed/19684887
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