Novel Roles of Hakai in Cell Proliferation and Oncogenesis

During tumor development, cells acquire multiple phenotypic changes upon misregulation of oncoproteins and tumor suppressor proteins. Hakai was originally identified as an E3 ubiquitin-ligase for the E-cadherin complex that regulates cell–cell contacts. Here, we present evidence that Hakai plays a c...

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Autores principales: Figueroa, Angélica, Kotani, Hirokazu, Toda, Yoshinobu, Mazan-Mamczarz, Krystyna, Mueller, Eva-Christina, Otto, Albrecht, Disch, Lena, Norman, Mark, Ramdasi, Rasika Mohan, Keshtgar, Mohammed, Gorospe, Myriam, Fujita, Yasuyuki
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2009
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719571/
https://ncbi.nlm.nih.gov/pubmed/19535458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-08-0845
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