Solution state structures of human pancreatic amylin and pramlintide

We have employed pramlintide (prAM) as a surrogate for hAM in CD and NMR studies of the conformational preferences of the N-terminal portion of the structure in media which do not provide long-lived monomeric solutions of hAM due to its rapid conversion to preamyloid β aggregate states. Direct compa...

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Bibliographic Details
Main Authors: Cort, John R., Liu, Zhihong, Lee, Gregory M., Huggins, K.N.L., Janes, Susan, Prickett, Kathryn, Andersen, Niels H.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2009
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Original articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719500/
https://ncbi.nlm.nih.gov/pubmed/19596697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzp029
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