Endogenous Truncated TrkB.T1 Receptor Regulates Neuronal Complexity and TrkB Kinase Receptor Function In Vivo

Pathological or in vitro overexpression of the truncated TrkB (TrkB.T1) receptor inhibits signaling through the full-length TrkB (TrkB.FL) tyrosine kinase receptor. However, to date, the role of endogenous TrkB.T1 is still unknown. By studying mice lacking the truncated TrkB.T1 isoform but retaining...

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Hlavní autoři: Carim-Todd, Laura, Bath, Kevin G., Fulgenzi, Gianluca, Yanpallewar, Sudhirkumar, Jing, Deqiang, Barrick, Colleen A., Becker, Jodi, Buckley, Hannah, Dorsey, Susan G., Lee, Francis S., Tessarollo, Lino
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719435/
https://ncbi.nlm.nih.gov/pubmed/19158294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5060-08.2009
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