Mechanism of Hypoxia-induced GCM1 Degradation: IMPLICATIONS FOR THE PATHOGENESIS OF PREECLAMPSIA

Preeclampsia is a major pregnancy-specific disorder affecting 5–7% of pregnancies worldwide. Although hypoxia caused by incomplete trophoblast invasion and impaired spiral arterial remodeling is thought to be a major cause of preeclampsia, how hypoxia affects placental development remains uncertain....

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Detalhes bibliográficos
Main Authors: Chiang, Meng-Hsiu, Liang, Feng-Yu, Chen, Chie-Pein, Chang, Ching-Wen, Cheong, Mei-Leng, Wang, Liang-Jie, Liang, Ching-Yeu, Lin, Fang-Yu, Chou, Chih-Chine, Chen, Hungwen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719381/
https://ncbi.nlm.nih.gov/pubmed/19416964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.016170
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