Thromboxane A(2) Receptor Activates a Rho-associated Kinase/LKB1/PTEN Pathway to Attenuate Endothelium Insulin Signaling

This study was conducted to elucidate the molecular mechanisms of thromboxane A2 receptor (TP)-induced insulin resistance in endothelial cells. Exposure of human umbilical vein endothelial cells (HUVECs) or mouse aortic endothelial cells to either IBOP or U46619, two structurally related thromboxane...

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Bibliografiska uppgifter
Huvudupphovsmän: Song, Ping, Zhang, Miao, Wang, Shuangxi, Xu, Jian, Choi, Hyoung Chul, Zou, Ming-Hui
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2009
Ämnen:
Mechanisms of Signal Transduction
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719350/
https://ncbi.nlm.nih.gov/pubmed/19403525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.012583
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