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The Polypyrimidine Tract-binding Protein Is Required for Efficient Dengue Virus Propagation and Associates with the Viral Replication Machinery

The polypyrimidine tract-binding protein (PTB) functions primarily as an IRES trans-acting factor in the propagation of hepatitis C virus and picornaviruses. PTB interacts with secondary structures within the 3′- and 5′-untranslated regions of these viral genomes to mediate efficient IRES-mediated v...

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Autors principals: Anwar, Azlinda, Leong, K. M., Ng, Mary L., Chu, Justin J. H., Garcia-Blanco, Mariano A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719340/
https://ncbi.nlm.nih.gov/pubmed/19380576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.006239
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