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Homeodomain Interacting Protein Kinase 2 Activation Compromises Endothelial Cell Response to Laminar Flow: Protective Role of p21(waf1,cip1,sdi1)

BACKGROUND: In the cardiovascular system, laminar shear stress (SS) is one of the most important source of endothelial protecting signals. Physical and chemical agents, however, including ionising radiations and anticancer drugs, may injure endothelial cells determining an increase in oxidative stre...

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Detalhes bibliográficos
Main Authors: Mattiussi, Stefania, Lazzari, Chiara, Truffa, Silvia, Antonini, Annalisa, Soddu, Silvia, Capogrossi, Maurizio C., Gaetano, Carlo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719102/
https://ncbi.nlm.nih.gov/pubmed/19668373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006603
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