Bevacizumab and carboplatin increase survival and asymptomatic tumor volume in a glioma model

To evaluate efficacy and MRI findings after intravenous bevacizumab and/or carboplatin in a human glioma animal model, we randomized male nude rats with intracerebral UW28 human glioma xenografts to four groups: (1) controls (n = 9), (2) bevacizumab 10 mg/kg (n = 6), (3) carboplatin 200 mg/m(2) (n =...

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Bibliografiske detaljer
Main Authors: Jahnke, Kristoph, Muldoon, Leslie L., Varallyay, Csanad G., Lewin, Seth J., Kraemer, Dale F., Neuwelt, Edward A.
Format: Artigo
Sprog:Inglês
Udgivet: Duke University Press 2009
Fag:
Basic and Translational Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718985/
https://ncbi.nlm.nih.gov/pubmed/18772353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-077
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