Antitumor effect in medulloblastoma cells by gefitinib: Ectopic HER2 overexpression enhances gefitinib effects in vivo

The effects of the epidermal growth factor receptor (EGFR) inhibitor gefitinib on cell growth and signaling were evaluated in three medulloblastoma (MB) cell lines (D283, D341, Daoy), one supratentorial primitive neuroectodermal tumor cell line (PFSK), and four MB primary cultures. Cell lines showed...

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Hlavní autoři: Meco, Daniela, Servidei, Tiziana, Riccardi, Anna, Ferlini, Cristiano, Cusano, Gabriella, Zannoni, Gian Franco, Giangaspero, Felice, Riccardi, Riccardo
Médium: Artigo
Jazyk:Inglês
Vydáno: Duke University Press 2009
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718969/
https://ncbi.nlm.nih.gov/pubmed/19033425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-095
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