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Axin expression in thymic stromal cells contributes to an age-related increase in thymic adiposity and is associated with reduced thymopoiesis independently of ghrelin signaling

The adipocytes are the predominant cell types that constitute the bulk of the thymic microenvironment by the fifth decade of life in healthy humans. An age-related increase in thymic adiposity is associated with reduced thymopoiesis and compromised immune surveillance in the elderly. However, the me...

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Detalhes bibliográficos
Main Authors: Yang, Hyunwon, Youm, Yun-Hee, Sun, Yuxiang, Rim, Jong-Seop, Galbán, Craig J., Vandanmagsar, Bolormaa, Dixit, Vishwa Deep
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718808/
https://ncbi.nlm.nih.gov/pubmed/19299626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1008621
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