Deficient Ghrelin Receptor-mediated Signaling Compromises Thymic Stromal Cell Microenvironment by Accelerating Thymic Adiposity

With progressive aging, adipocytes are the major cell types that constitute the bulk of thymic microenvironment. Understanding the origin of thymic adipocytes and mechanisms responsible for age-related thymic adiposity is thus germane for the design of long lasting thymic rejuvenation strategies. We...

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Hlavní autoři: Youm, Yun-Hee, Yang, Hyunwon, Sun, Yuxiang, Smith, Roy G., Manley, Nancy R., Vandanmagsar, Bolormaa, Dixit, Vishwa Deep
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Molecular Basis of Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652314/
https://ncbi.nlm.nih.gov/pubmed/19054770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808302200
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