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Apical sorting of a voltage- and Ca(2+)-activated K(+) channel α-subunit in Madin-Darby canine kidney cells is independent of N-glycosylation

The voltage- and Ca(2+)-activated K(+) (K(V,Ca)) channel is expressed in a variety of polarized epithelial cells seemingly displaying a tissue-dependent apical-to-basolateral regionalization, as revealed by electrophysiology. Using domain-specific biotinylation and immunofluorescence we show that th...

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Main Authors: Bravo-Zehnder, Marcela, Orio, Patricio, Norambuena, Andrés, Wallner, Martin, Meera, Pratap, Toro, Ligia, Latorre, Ramón, González, Alfonso
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC27187/
https://ncbi.nlm.nih.gov/pubmed/11069304
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