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Selective Alterations in Biosynthetic and Endocytic Protein Traffic in Madin-Darby Canine Kidney Epithelial Cells Expressing Mutants of the Small GTPase Rac1

Madin-Darby canine kidney (MDCK) cells expressing constitutively active Rac1 (Rac1V12) accumulate a large central aggregate of membranes beneath the apical membrane that contains filamentous actin, Rac1V12, rab11, and the resident apical membrane protein GP-135. To examine the roles of Rac1 in membr...

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Bibliographische Detailangaben
Hauptverfasser: Jou, Tzuu-Shuh, Leung, Som-Ming, Fung, Linette M., Ruiz, Wily G., Nelson, W. James, Apodaca, Gerard
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC14775/
https://ncbi.nlm.nih.gov/pubmed/10637309
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