Aging and Environmental Exposures Alter Tissue-Specific DNA Methylation Dependent upon CpG Island Context

Epigenetic control of gene transcription is critical for normal human development and cellular differentiation. While alterations of epigenetic marks such as DNA methylation have been linked to cancers and many other human diseases, interindividual epigenetic variations in normal tissues due to agin...

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Main Authors: Christensen, Brock C., Houseman, E. Andres, Marsit, Carmen J., Zheng, Shichun, Wrensch, Margaret R., Wiemels, Joseph L., Nelson, Heather H., Karagas, Margaret R., Padbury, James F., Bueno, Raphael, Sugarbaker, David J., Yeh, Ru-Fang, Wiencke, John K., Kelsey, Karl T.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718614/
https://ncbi.nlm.nih.gov/pubmed/19680444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000602
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