Chromatin restoration following nucleotide excision repair involves the incorporation of ubiquitinated H2A at damaged genomic sites

Restoration of functionally intact chromatin structure following DNA damage processing is crucial for maintaining genetic and epigenetic information in human cells. Here, we show the UV-induced uH2A foci formation in cells lacking XPC, DDB2, CSA or CSB, but not in cells lacking XPA, XPG or XPF indic...

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Huvudupphovsmän: Zhu, Qianzheng, Wani, Gulzar, Arab, Hany H., El-Mahdy, Mohamed A., Ray, Alo, Wani, Altaf A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718537/
https://ncbi.nlm.nih.gov/pubmed/19059499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.11.007
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