Gene Expression Analysis of an EGFR Indirectly Related Pathway Identified PTEN and MMP9 as Reliable Diagnostic Markers for Human Glial Tumor Specimens

In this study the mRNA levels of five EGFR indirectly related genes, EGFR, HB-EGF, ADAM17, PTEN, and MMP9, have been assessed by Real-time PCR in a panel of 37 glioblastoma multiforme specimens and in 5 normal brain samples; as a result, in glioblastoma, ADAM17 and PTEN expression was significantly...

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Bibliografiske detaljer
Main Authors: Comincini, Sergio, Paolillo, Mayra, Barbieri, Giulia, Palumbo, Silvia, Sbalchiero, Elena, Azzalin, Alberto, Russo, Marika A., Schinelli, Sergio
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2009
Fag:
Methodology Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718324/
https://ncbi.nlm.nih.gov/pubmed/19657395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/924565
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