Gene Expression Analysis of an EGFR Indirectly Related Pathway Identified PTEN and MMP9 as Reliable Diagnostic Markers for Human Glial Tumor Specimens

In this study the mRNA levels of five EGFR indirectly related genes, EGFR, HB-EGF, ADAM17, PTEN, and MMP9, have been assessed by Real-time PCR in a panel of 37 glioblastoma multiforme specimens and in 5 normal brain samples; as a result, in glioblastoma, ADAM17 and PTEN expression was significantly...

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מידע ביבליוגרפי
Main Authors: Comincini, Sergio, Paolillo, Mayra, Barbieri, Giulia, Palumbo, Silvia, Sbalchiero, Elena, Azzalin, Alberto, Russo, Marika A., Schinelli, Sergio
פורמט: Artigo
שפה:Inglês
יצא לאור: Hindawi Publishing Corporation 2009
נושאים:
Methodology Report
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718324/
https://ncbi.nlm.nih.gov/pubmed/19657395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/924565
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