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Gene Expression Analysis of an EGFR Indirectly Related Pathway Identified PTEN and MMP9 as Reliable Diagnostic Markers for Human Glial Tumor Specimens

In this study the mRNA levels of five EGFR indirectly related genes, EGFR, HB-EGF, ADAM17, PTEN, and MMP9, have been assessed by Real-time PCR in a panel of 37 glioblastoma multiforme specimens and in 5 normal brain samples; as a result, in glioblastoma, ADAM17 and PTEN expression was significantly...

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主要な著者: Comincini, Sergio, Paolillo, Mayra, Barbieri, Giulia, Palumbo, Silvia, Sbalchiero, Elena, Azzalin, Alberto, Russo, Marika A., Schinelli, Sergio
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi Publishing Corporation 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718324/
https://ncbi.nlm.nih.gov/pubmed/19657395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/924565
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