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Transitions between Closed and Open Conformations of TolC: The Effects of Ions in Simulations
Bacteria, such as Escherichia coli, use multidrug efflux pumps to export toxic substrates through their cell membranes. Upon formation of an efflux pump, the aperture of its outer membrane protein TolC opens and thereby enables the extrusion of substrate molecules. The specialty of TolC is its abili...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2718315/ https://ncbi.nlm.nih.gov/pubmed/19383457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.01.021 |
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