Intracellular domains interactions and gated motions of I(KS) potassium channel subunits

Voltage-gated K(+) channels co-assemble with auxiliary β subunits to form macromolecular complexes. In heart, assembly of Kv7.1 pore-forming subunits with KCNE1 β subunits generates the repolarizing K(+) current I(KS). However, the detailed nature of their interface remains unknown. Mutations in eit...

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Detalhes bibliográficos
Main Authors: Haitin, Yoni, Wiener, Reuven, Shaham, Dana, Peretz, Asher, Cohen, Enbal Ben-Tal, Shamgar, Liora, Pongs, Olaf, Hirsch, Joel A, Attali, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718281/
https://ncbi.nlm.nih.gov/pubmed/19521339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.157
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