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Histone Octamer Helical Tubes Suggest that an Internucleosomal Four-Helix Bundle Stabilizes the Chromatin Fiber

A major question in chromatin involves the exact organization of nucleosomes within the 30-nm chromatin fiber and its structural determinants of assembly. Here we investigate the structure of histone octamer helical tubes via the method of iterative helical real-space reconstruction. Accurate placem...

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Autors principals: Frouws, Timothy D., Patterton, Hugh-G., Sewell, Bryan T.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718273/
https://ncbi.nlm.nih.gov/pubmed/19383479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.10.075
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